• Scientist III Bioassay, AR&D

    Location US-NJ-Piscataway
    Posted Date 1 week ago(1 week ago)
    ID
    2018-2192
    Company
    Adello Biologics, LLC
  • Overview

    Adello Biologics is a privately held, U.S.-based biotechnology company that leads with science to accelerate development and drive manufacturing efficiency. The company's aim is to provide high-quality, affordable biosimilars to patients worldwide. Headquartered in Piscataway, NJ and driven by a team of highly skilled industry veterans, Adello is advancing a strategic pipeline of proteins and complex monoclonal antibodies with lead candidates in oncology and immunology. For more information, visit www.Adellobio.com

     

    Our vision is to make biosimilar medications affordable. We are seeking candidates interested in contributing to a bourgeoning field that has the potential to help millions of patients. As a growing company, Adello Biologics offers real development opportunities for candidates excited to take on responsibility, make an immediate impact and help us achieve our vision. As part of a close knit team, you’ll have the opportunity to work in a unique, high science industry while expanding your career. We are seeking a Scientist III Bioassay, AR&D to be based out of our HQ in Piscataway, NJ.

    Responsibilities

    SUMMARY:

    The Scientist III Bioassay will be responsible for phase specific analytical method development and sample testing required for functional characterization of biologics through various phases of biosimilar development. Additional responsibilities include support of method transfer to QC laboratories and liaising with CRO laboratories. Techniques employed include but are not limited to cell based assays, ELISA and SPR binding assays. Experience with flow-cytometry and BLI binding assays is a plus. The candidate must have experience authoring SOPs and technical reports. The successful candidate will be a highly motivated, well-organized, and detail-oriented scientist who can work effectively in a fast-paced and multi-disciplinary environment.

     

    ESSENTIAL DUTIES AND RESPONSIBILITIES

     

    • Development of bioassays for characterization and product release: binding, potency, effector function assays, downstream signaling, reverse-signaling, etc.
    • Support drug substance and drug product manufacturing process development
    • Elucidation of structure/function relationships for biologic therapeutics
    • Transfer of analytical methodologies to other laboratories
    • Maintain a detailed and well-organized record of all laboratory activities
    • Author SOPs and technical reports
    • Participate and/or lead cross-functional project teams
    • Represent the company in discussions with external parties as needed
    • Participate in lab maintenance activities as needed

    Qualifications

    PREREQUISITES:

    Education:

    • Minimum B.S. degree in Analytical Chemistry, Biophysical/biochemical sciences, pharmaceutical sciences with 12 years of industry experience
    • Or Master’s Degree in Biochemistry, Biotechnology, Biology with 10 years of industry experience
    • Or Ph.D. in Cell Biology, Biochemistry, Biotechnology, Biology with 5-8 years of experience

    Experience:

    • Strong experience in analytical method development and validation
    • Firm understanding of cellular pathways and mechanisms of drug action
    • Familiar with ICH guidelines and USP/EP pharmacopeia requirements
    • A strong theoretical understanding and experience in protein chemistry

     

    SPECIALIZED KNOWLEDGE AND SKILLS:

    • Experience with MS office tool is required
    • Experience with DOE software and statistical data analysis is a plus
    • Strong communication and technical writing skills

     

    WORK ENVIRONMENT AND PHYSICAL DEMANDS:

    General Work Environment:

    • 70% laboratory and 30% office setting
    • Extended hours or weekend hours may be occasionally necessary

     

    Noise:

    • No extraordinary noise levels

     

    Standing/Lifting:

    • No extraordinary requirements

     

    Visual:

    • No extraordinary requirements

     

    Stress:

    • High paced demanding environment

     

    Travel:

    • Less than 30%

     

    Adello Biologics, LLC provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to race, color, religion, sex, national origin, age, disability or genetics. In addition to federal law requirements, Adello Biologics, LLC complies with applicable state and local laws governing nondiscrimination in employment in every location in which the company has facilities. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, and transfer, leaves of absence, compensation and training.

    Notice To Agency And Search Firm Representatives  

    Adello Biologics is not accepting unsolicited resumes from agencies and/or search firms for this job posting. Resumes submitted to any Adello employee by a third party agency and/or search firm without a valid written & signed search agreement, will become the sole property of Adello. No fee will be paid if a candidate is hired for this position as a result of an unsolicited agency or search firm referral. Thank you.

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